How to seal screw holes?

[CPHILHOWER]

I have a sealed box with a pair of 15's. Had grill with the clamps. One of the clamps broke. Removed the clamp/grill assemblies. Can I just put the screws back into the holes? Or do I need to seal them and how?
Thanks
Chris

[exalted512]

ive had the screws on my subs in and out SEVERAL times
it wouldnt hurt if you can get some wood filler or wood glue and put it in the hole if you can get it in there...i would let it dry before you put the screw in first, otherwise you might never get it out...
-Cody

[CPHILHOWER]

The grills are gone. Just the holes. I put the screws back in for now.
Chris